JMJD6 promotes melanoma carcinogenesis through regulation of the alternative splicing of PAK1, a key MAPK signaling component.
Xujun LiuWenzhe SiXinhua LiuLin HeJie RenZiran YangJianguo YangWanjin LiShumeng LiuFei PeiXiaohan YangLuyang SunPublished in: Molecular cancer (2017)
Our results indicate that JMJD6 is critically involved in melanoma carcinogenesis, supporting the pursuit of JMJD6 as a potential biomarker for melanoma aggressiveness and a target for melanoma intervention.