From Spinal Ependymoma to Superficial Siderosis: A Bottom to Top Cause of Progressive Neurological Deterioration.
Diana Vilares ValenteInês GilHipólito NzwaloCatarina FelixPublished in: The Neurohospitalist (2024)
Superficial siderosis (SS) is an infrequent condition characterized by hemosiderin deposition in the central nervous system, resulting from chronic subarachnoid hemorrhage, often linked to dural mater diseases. Through a case report of a 50-year-old male with severe sensorineural hearing loss and newly diagnosed epilepsy, we explore SS triggered by a spinal ependymoma, diagnosed via resonance magnetic imaging (MRI). This case highlights the necessity of comprehensive neuroaxis imaging to identify treatable etiologies. The complexity of SS, with its varied clinical presentations, necessitates early detection and a multidisciplinary treatment approach. Despite limited treatment options and the uncertain efficacy of therapies like deferiprone, early intervention is crucial for mitigating irreversible neurological damage and enhancing patient prognosis.
Keyphrases
- subarachnoid hemorrhage
- cerebral ischemia
- newly diagnosed
- brain injury
- high resolution
- spinal cord
- randomized controlled trial
- magnetic resonance imaging
- multiple sclerosis
- oxidative stress
- early onset
- blood brain barrier
- quality improvement
- energy transfer
- combination therapy
- photodynamic therapy
- quantum dots
- molecularly imprinted