Comorbidity and response to TNF inhibitors in axial spondyloarthritis: longitudinal analysis of the BSRBR-AS.
Sizheng Steven ZhaoGareth T JonesGary John MacfarlaneDavid M HughesRobert John MootsNicola J GoodsonPublished in: Rheumatology (Oxford, England) (2021)
Participants with multiple comorbidities had poorer treatment outcomes, particularly increased treatment discontinuation and poorer improvements in function and quality of life. These results inform clinicians and educate patients about response to the first TNFi given comorbidity burden.