Comorbidity and response to TNF inhibitors in axial spondyloarthritis: longitudinal analysis of the BSRBR-AS.

Sizheng Steven Zhao Gareth T Jones Gary John MacfarlaneDavid M HughesRobert John MootsNicola J Goodson

Published in: Rheumatology (Oxford, England) (2021)

Participants with multiple comorbidities had poorer treatment outcomes, particularly increased treatment discontinuation and poorer improvements in function and quality of life. These results inform clinicians and educate patients about response to the first TNFi given comorbidity burden.

Keyphrases

end stage renal disease
ejection fraction
newly diagnosed
chronic kidney disease
rheumatoid arthritis
peritoneal dialysis
prognostic factors
cross sectional
disease activity