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Transcriptomic signatures of tumors undergoing T cell attack.

Aishwarya GokuldassAimilia SchinaMartin LaussKatja HarbstChristopher Aled ChamberlainArianna DraghiMarie Christine Wulff WestergaardMorten NielsenKrisztian PappZsofia SztupinszkiIstvan CsabaiInge Marie SvaneZoltan SzallasiGöran JönssonMarco Donia
Published in: Cancer immunology, immunotherapy : CII (2021)
The TuTack scores measure the effects on tumor cells of an anti-tumor immune response and represent a comprehensive method to identify immunologically responsive tumors. Our findings suggest that TuTack may allow patient selection in immunotherapy clinical trials and warrant its application in multimodal biomarker strategies.
Keyphrases
  • immune response
  • clinical trial
  • case report
  • single cell
  • genome wide
  • cancer therapy
  • pain management
  • rna seq
  • toll like receptor
  • randomized controlled trial
  • inflammatory response