Mixed adenoneuroendocrine carcinoma with loss of HER2 positivity after trastuzumab-based chemotherapy for HER2-positive gastric cancer: a case report.

Hiromi NagataHironori TsujimotoYoshihisa YaguchiKeita KouzuYujiro ItazakiYusuke IshibashiSatoshi TsuchiyaTakao SugiharaNozomi ItoManabu HaradaShinsuke NomuraYoshitaka UtsumiHideyuki ShimazakiYoji KishiHideki Ueno

Published in: Surgical case reports (2020)

We encountered a rare case of rapidly progressive mixed adenoneuroendocrine carcinoma that was negative for HER2 expression after T-mab treatment combined with chemotherapy.

Keyphrases

rare case
locally advanced
poor prognosis
multiple sclerosis
epidermal growth factor receptor
rectal cancer
metastatic breast cancer