The dynamics of endothelial changes in vivo following standardized skin injury.
Sabina Catharina Andrea HanssenRomy Rosa Maria Catharina KeijsersAnke Gertruda Martina HendriksMarieke Martha Benedicta SeygerCatharina Joanna Maria van der VleutenPeter Cornelis Maria van de KerkhofPublished in: Skin research and technology : official journal of International Society for Bioengineering and the Skin (ISBS) [and] International Society for Digital Imaging of Skin (ISDIS) [and] International Society for Skin Imaging (ISSI) (2019)
Endothelial cell proliferation and HIF-1α expression appear to be (strongly) related, having maximum levels at 16 hours and 72 hours. Angiogenesis and HIF-1α expression are not continuous processes, but rather occur intermittently.