Clinical spectrum of rectal cancer identifies hallmarks of early-onset patients and next-generation treatment strategies.
Dingcheng ShenPuning WangYumo XieZhuokai ZhuangMingxuan ZhuXiaolin WangMeijin HuangYanxin LuoHuichuan YuPublished in: Cancer medicine (2022)
Early-onset rectal cancers are distinct from late-onset cases in clinicopathological features, treatment modalities, and outcomes. The clinical trials and studies that are specific for young populations are needed to develop optimal strategies for cancer screening, treatment, and surveillance.
Keyphrases
- early onset
- late onset
- rectal cancer
- clinical trial
- end stage renal disease
- newly diagnosed
- ejection fraction
- public health
- chronic kidney disease
- randomized controlled trial
- peritoneal dialysis
- type diabetes
- prognostic factors
- gene expression
- squamous cell carcinoma
- metabolic syndrome
- radiation therapy
- papillary thyroid
- weight loss
- middle aged
- patient reported outcomes
- glycemic control