Pilot evaluation of an enzymatic assay for rapid measurement of antiretroviral drug concentrations.
Ayokunle O OlanrewajuBenjamin P SullivanAshley R BardonTiffany J LoTim R CresseyJonathan D PosnerPaul K DrainPublished in: Virology journal (2021)
This novel enzymatic assay for measuring HIV reverse transcriptase activity may be suitable for distinguishing TFV-DP concentrations in blood that correspond to protective PrEP adherence.
Keyphrases
- hiv positive
- men who have sex with men
- hiv infected
- human immunodeficiency virus
- hiv aids
- antiretroviral therapy
- high throughput
- hiv testing
- hydrogen peroxide
- hiv infected patients
- hepatitis c virus
- south africa
- study protocol
- randomized controlled trial
- clinical trial
- adverse drug
- adipose tissue
- nitric oxide
- glycemic control