Analysis of Immunohistochemical Expression of BRAF (V600E) Mutation in Serrated Colorectal Polyps: A Study from Tertiary Hospital in Oman.

Abir Al GhafriShayma G Sayed Suad Al Badi Afrah Al Rashdi Samya Al HusainiAsim QureshiAsem Shalaby

Published in: Asian Pacific journal of cancer prevention : APJCP (2024)

Serrated polyps are now well known for their potential to develop CRC. Immunohistochemistry is an easy and reproducible way to detect BRAF (V600E) mutation. Our study showed there is high prevalence (64.3%) of BRAF mutation in serrated polyps in the Omani population. The majority of these polyps- were HP and SSL; and ≤5 mm in size and located in the distal colon.

Keyphrases

chronic rhinosinusitis
metastatic colorectal cancer
wild type
poor prognosis
minimally invasive
long non coding rna
risk assessment