Sonic hedgehog signalling proteins are frequently expressed in retinoblastoma and are associated with aggressive clinicopathological features.
Ji-Young ChoeJi Yun YunYoon Kyung JeonSe-Hoon KimHo-Kyung ChoungSohee OhMira ParkJi Eun KimPublished in: Journal of clinical pathology (2014)
SHH signalling molecules were frequently expressed in retinoblastoma tumour cells, and high SHH expression was closely related to an advanced disease status. Our results suggest that the SHH signalling pathway may play a role in the progression of retinoblastoma.