Integrated pan-cancer of AURKA expression and drug sensitivity analysis reveals increased expression of AURKA is responsible for drug resistance.

Noushin MiralaeiAhmad MajdKamran Ghaedi Maryam PeymaniMasoomeh Safaei

Published in: Cancer medicine (2021)

Increased expression of AURKA is observed in prevalent cancers and associated with poor prognostic and the development of drug resistance. In addition, some chemotherapy drugs can reduce the expression of this gene.

Keyphrases

poor prognosis
long non coding rna
emergency department
gene expression
dna methylation
papillary thyroid
young adults
transcription factor