Prognostic Value of MicroRNAs in Stage II Colorectal Cancer Patients: A Systematic Review and Meta-Analysis.

Shanthi SabarimuruganMadurantakam Royam MadhavChellan KumarasamyAjay GuptaSiddharta BaxiSunil KrishnanRama Jayaraj

Published in: Molecular diagnosis & therapy (2021)

MicroRNAs play a significant role in determining prognosis in stage II CRC patients, with upregulation of miR21, miR215, miR143-5p and miR106a, in particular, portending a worse prognosis. These miRNAs could be considered for further evaluation as biomarkers of prognosis and to guide the decision to administer adjuvant chemotherapy.

Keyphrases

cell proliferation
long non coding rna
long noncoding rna
end stage renal disease
poor prognosis
ejection fraction
chronic kidney disease
newly diagnosed
peritoneal dialysis
prognostic factors
signaling pathway
patient reported