A predictive model for conversion to psychosis in clinical high-risk patients.
Adam J CiarleglioGary BrucatoMichael D MasucciRebecca AltschulerTiziano ColibazziCheryl M CorcoranFrancesca M CrumpGuillermo HorgaEugénie Lehembre-ShiahWei LeongScott A SchobelMelanie M WallLawrence H YangJeffrey A LiebermanRagy R GirgisPublished in: Psychological medicine (2018)
The prediction model performed well in classifying converters and non-converters and revealed SIPS measures that are relatively strong predictors of conversion, comparable with the risk calculator published by NAPLS (c-index = 0.71), but requiring only a structured clinical interview. Future work will seek to externally validate the model and enhance its performance with the incorporation of relevant biomarkers.