Leukocyte cell-derived chemotaxin 2 promotes the development of nonalcoholic fatty liver disease through STAT-1 pathway in mice.

Jinghua WangYishu ChenRan PanChao WuShenghui ChenLan LiYou-Ming LiChaohui YuZhuo-Xian MengCheng-Fu Xu

Published in: Liver international : official journal of the International Association for the Study of the Liver (2021)

LECT2 expression is significantly elevated in NAFLD. LECT2 induces the occurrence and development of NAFLD through the STAT-1 pathway. LECT2 may be a potential therapeutic target for NAFLD.

Keyphrases

cell proliferation
poor prognosis
risk assessment
type diabetes
metabolic syndrome
high fat diet induced
insulin resistance
climate change