Australian Parkinson's Genetics Study (APGS): pilot (n=1532).

Svetlana Bivol George D Mellick Jacob Gratten Richard ParkerAoibhe MulcahyPhilip E Mosley Peter C Poortvliet Adrian I Campos Brittany L Mitchell Luis M García-MarínSimone CrossMary FergusonPenelope A LindDanuta Z LoeschPeter M Visscher Sarah E Medland Clemens R Scherzer Nicholas G Martin Miguel E Renteria

Published in: BMJ open (2022)

We plan to recruit sex-matched and age-matched unaffected controls, genotype all participants and collect non-motor symptoms and cognitive function data. Future work will explore the role of genetic and environmental factors in the aetiology of PD susceptibility, onset, symptoms, and progression, including as part of international PD research consortia.

Keyphrases

sleep quality
electronic health record
current status
big data
randomized controlled trial
machine learning
clinical trial
copy number
double blind