Integrated information in the EEG of preterm infants increases with family nurture intervention, age, and conscious state.
Joseph R IslerRaymond I StarkPhilip G GrieveMartha G WelchMichael M MyersPublished in: PloS one (2018)
A putative quantifier of consciousness, integrated information, was applied to preterm infant EEG data after novel pre-processing. Integrated information had a non-random structure as a function of the time lag over which it was computed. For most lags, it increased with age in early life, but even more so in infants exposed to Family Nurture Intervention (FNI), providing further evidence that FNI advances brain maturation in preterm infants. Also, it discriminated between conscious states (awake, REM sleep, NREM sleep), providing empirical support for the Integrated Information Theory of Consciousness in human infants.
Keyphrases
- preterm infants
- low birth weight
- early life
- resting state
- randomized controlled trial
- health information
- functional connectivity
- endothelial cells
- working memory
- physical activity
- sleep quality
- healthcare
- electronic health record
- magnetic resonance imaging
- multiple sclerosis
- machine learning
- depressive symptoms
- preterm birth
- diffusion weighted imaging
- blood brain barrier