Neuroprotective Effects of Intermittent Theta Burst Stimulation in Parkinson's Disease (NET-PD): A Study Protocol for a Delayed-Start Randomized Double-Blind Sham-Controlled Trial.
Puyu LiNingdi LuoSainan SunYuanyuan LiDingding ShenXue ZhuLiche ZhouHaiyan ZhouLiche ZhouPublished in: Journal of clinical medicine (2022)
Previous research has demonstrated a rudimentary method for assessing and delaying PD progression in clinical medication trials. The NET-PD study adopts a rigorous methodology and specific disease-modifying designs to demonstrate the neuroprotective effect of iTBS on PD and investigate the potential mechanism of iTBS in regulating brain and motor functions. We hope to provide supposition for the subsequent exploration of diverse neuroprotection methods.
Keyphrases
- double blind
- placebo controlled
- clinical trial
- cerebral ischemia
- open label
- phase iii
- study protocol
- phase ii
- healthcare
- randomized controlled trial
- working memory
- high intensity
- white matter
- blood brain barrier
- transcranial magnetic stimulation
- emergency department
- multiple sclerosis
- subarachnoid hemorrhage
- adverse drug
- drug induced