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Persistent orbital inflammation following complete excision of deep dermoid cysts.

Caroline L WildeKaveh VahdaniCaroline ThaungGeoffrey E Rose
Published in: Orbit (Amsterdam, Netherlands) (2022)
Piecemeal excision of dermoid cysts carries the risk of implanting epithelial fragments into orbital fat, which is well recognized to continue secreting oily debris, inciting chronic, often granulomatous inflammation. The authors present the clinical and histological details for two patients with persistent lipogranulomatous inflammation for years after piecemeal excision of deep orbital dermoid cysts, in the absence of any residual epithelium. The importance of copious saline lavage - to 'float-out" and reduce microscopic lipid droplets - is also emphasised.
Keyphrases
  • oxidative stress
  • adipose tissue
  • fatty acid
  • rheumatoid arthritis
  • interstitial lung disease
  • idiopathic pulmonary fibrosis