Dysregulation of mitochondrial function and biogenesis modulators in adipose tissue of obese children.

R Zamora-MendozaH Rosas-VargasM T Ramos-CervantesP Garcia-ZunigaH Perez-LorenzanaP Mendoza-LorenzoAndric C Perez-OrtizF J Estrada-MenaA Miliar-GarciaE Lara-PadillaG CeballosA RodriguezF VillarrealI Ramirez-Sanchez

Published in: International journal of obesity (2005) (2017)

Adipose tissue from children with obesity demonstrates a dysregulation of key modulators of MB and organelle structure, and displays hyperacetylation of key proteins and altered expression of upstream regulators of cell metabolism.

Keyphrases

adipose tissue
insulin resistance
small molecule
young adults
high fat diet
metabolic syndrome
weight loss
type diabetes
poor prognosis
single cell
high fat diet induced
cell therapy
transcription factor
body mass index
weight gain
bariatric surgery
physical activity
skeletal muscle
mesenchymal stem cells