Comparison of the efficacy of equivalent doses of dexamethasone, methylprednisolone, and hydrocortisone for treatment of COVID-19-related acute respiratory distress syndrome: a prospective three-arm randomized clinical trial.

Abbas TaherMarjan LashkariFariba KeramatSeyyed Hamid HashemiLadan SedighiJalal PoorolajalMaryam Mehrpooya

Published in: Wiener medizinische Wochenschrift (1946) (2023)

Based on the results, severe cases of COVID-19 treated with dexamethasone might have a better clinical status at 28-day follow-up compared to methylprednisolone and hydrocortisone at an equivalent dose. Larger multicenter trials are required to confirm our findings.

Keyphrases

acute respiratory distress syndrome
high dose
coronavirus disease
sars cov
extracorporeal membrane oxygenation
mechanical ventilation
low dose
septic shock
double blind
respiratory syndrome coronavirus
cross sectional
drug induced