Advanced MRI Techniques: Diagnosis and Follow-Up of Multiple Sclerosis.
Riccardo NistriAntonio IannielloValeria PozzilliCostanza GiannìCarlo PozzilliPublished in: Diagnostics (Basel, Switzerland) (2024)
Brain and spinal cord imaging plays a pivotal role in aiding clinicians with the diagnosis and monitoring of multiple sclerosis. Nevertheless, the significance of magnetic resonance imaging in MS extends beyond its clinical utility. Advanced imaging modalities have facilitated the in vivo detection of various components of MS pathogenesis, and, in recent years, MRI biomarkers have been utilized to assess the response of patients with relapsing-remitting MS to the available treatments. Similarly, MRI indicators of neurodegeneration demonstrate potential as primary and secondary endpoints in clinical trials targeting progressive phenotypes. This review aims to provide an overview of the latest advancements in brain and spinal cord neuroimaging in MS.
Keyphrases
- multiple sclerosis
- white matter
- spinal cord
- contrast enhanced
- magnetic resonance imaging
- clinical trial
- high resolution
- spinal cord injury
- diffusion weighted imaging
- neuropathic pain
- resting state
- mass spectrometry
- magnetic resonance
- computed tomography
- randomized controlled trial
- cerebral ischemia
- risk assessment
- cancer therapy
- photodynamic therapy
- disease activity
- study protocol