ATH434 Reduces α-Synuclein-Related Neurodegeneration in a Murine Model of Multiple System Atrophy.
Antonio Heras-GarvinVioletta RefoloClaudio SchmidtKatja MalfertheinerGregor K WenningMargaret BradburyDavid StamlerNadia StefanovaPublished in: Movement disorders : official journal of the Movement Disorder Society (2021)
Our findings demonstrate the beneficial disease-modifying effect of ATH434 in oligodendroglial α-synucleinopathy on both the motor phenotype and neurodegenerative pathology in the PLP-α-syn transgenic mouse and support the development of ATH434 for MSA. © 2021 The Authors. Movement Disorders published by Wiley Periodicals LLC on behalf of International Parkinson and Movement Disorder Society.