Adjuvant Radiation after Primary Resection of Atypical Lipomatous Tumors of the Extremity Reduces Local Recurrence but Increases Complications: A Multicenter Evaluation.

Joshua M LawrenzSamuel R JohnsonKevin ZhuMallory McKeonCullen P MoranJose VegaKatherine S HajduJames P NorrisLeo Y LuoEric T ShinoharaJustin Merrill Marken Cates Brian P RubinJohn D ReithJennifer L HalpernNathan W MeskoHerbert S SchwartzLukas M NystromGinger E Holt

Published in: Sarcoma (2022)

Adjuvant radiation after first-time resection of an ALT of the extremity was associated with a significantly reduced risk of local recurrence but a three-fold increase in complication rate. These data support a 10-year follow-up for these patients and inform a notable clinical trade-off if considering adjuvant radiation for this tumor with recurrent potential.

Keyphrases

early stage
end stage renal disease
chronic kidney disease
newly diagnosed
peritoneal dialysis
radiation induced
soft tissue
free survival
risk factors
cross sectional
radiation therapy
risk assessment
machine learning
patient reported outcomes
double blind
climate change
data analysis