Subdermal Ultrasound Contrast Agent Injection for Sentinel Lymph Node Identification: An Analysis of Safety and Contrast Agent Dose in Healthy Volunteers.

Priscilla MachadoMaria StanczakJi-Bin LiuJason N MooreJohn R EisenbreyLaurence NeedlemanWalter K KraftFlemming Forsberg

Published in: Journal of ultrasound in medicine : official journal of the American Institute of Ultrasound in Medicine (2017)

The subdermal use of Sonazoid in this study showed only minor local and nonsignificant AEs that were completely resolved without any intervention. Two different doses were compared with no significant differences observed between them. Hence, the lower dose studied (1 mL) was selected for use in future clinical studies.

Keyphrases

sentinel lymph node
magnetic resonance
lymph node
early stage
randomized controlled trial
neoadjuvant chemotherapy
ultrasound guided
magnetic resonance imaging
contrast enhanced
current status
computed tomography
squamous cell carcinoma
bioinformatics analysis
solid state