Thyme extract could overcome diabetes-induced reproductive dysfunction by inhibiting oxidative damage and increasing the expression of insulin receptor substrate and pyruvate kinase in the rat sperm.
Mahdieh RaeeszadehBorhan ShokrollahiAbolfazl AkbariSima MasumiAli Akbar AmiriPublished in: The Journal of pharmacy and pharmacology (2023)
In conclusion, thymol appears to alleviate diabetes-induced reproductive dysfunction by inhibiting oxidative damage, improving the metabolic state, and upregulating the expression of IRS and PK genes in the sperm of male rats.