Elucidating the Gene Signatures and Immune Cell Types in HIV-Infected Immunological Non-Responders by Bioinformatics Analyses.
Qing XiaoJunyan HanFengting YuLiting YanQun LiXiaojie LaoHongxin ZhaoFujie ZhangPublished in: International journal of general medicine (2022)
In this study, we suggested that the process of PIR might be related to TNF, CXCR4, TFRC, CD48, and IL7R. And these IRGs play roles in regulating immune-competent cells. And our constructed diagnostic model has excellent effectiveness. Moreover, some small-molecule drugs are screened to alleviate PIR.
Keyphrases
- small molecule
- hiv infected
- induced apoptosis
- genome wide
- randomized controlled trial
- rheumatoid arthritis
- antiretroviral therapy
- systematic review
- cell cycle arrest
- wastewater treatment
- dna methylation
- endoplasmic reticulum stress
- human immunodeficiency virus
- oxidative stress
- cell migration
- hepatitis c virus
- pi k akt
- genome wide analysis