Breastfeeding promotes early neonatal regulatory T-cell expansion and immune tolerance of non-inherited maternal antigens.

Hannah WoodAnimesh AcharjeeHayden PearceMohammed Nabil QuraishiRichard PowellAmanda RossiterAndrew BeggsAndrew EwerPaul MossGergely Toldi

Published in: Allergy (2021)

These data indicate that exposure of the neonate to maternal cells through breastfeeding acts to drive the maturation of Tregs and 'tolerizes' the neonate towards NIMA.

Keyphrases

preterm infants
birth weight
induced apoptosis
pregnancy outcomes
cell cycle arrest
electronic health record
transcription factor
dendritic cells
endoplasmic reticulum stress
big data
signaling pathway
gestational age
machine learning
cell death
deep learning