In vivo study revealed pro-tumorigenic effect of CMTM3 in hepatocellular carcinoma involving the regulation of peroxisome proliferator-activated receptor gamma (PPARγ).
Jiahui WangHongjin ChuZhixin WangXuebo WangXuexia LiuZhan SongFujun LiuPublished in: Cellular oncology (Dordrecht) (2022)
This study clarified the pro-tumorigenesis role of CMTM3 in HCC in vivo, possibly through the upregulation of PPARγ and activation of the PPAR pathway.