Retinal and circulating miRNA expression patterns in diabetic retinopathy: An in silico and in vivo approach.

Chiara Bianca Maria PlataniaRosa MaistoMaria Consiglia TrottaMichele D'AmicoSettimio RossiCarlo GesualdoGiovanbattista D'AmicoCornel BaltaHildegard HermanAnca HermeneanFranca FerraraccioIacopo PanareseFilippo DragoClaudio Bucolo

Published in: British journal of pharmacology (2019)

Serum and retina of diabetic mice express eight dysregulated miRNAs, which modified the expression of VEGF, BDNF, PPAR-α, and CREB1, before vasculopathy in diabetic retinas.

Keyphrases

diabetic retinopathy
optical coherence tomography
poor prognosis
type diabetes
binding protein
endothelial cells
molecular docking
vascular endothelial growth factor
long non coding rna