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Retinal and circulating miRNA expression patterns in diabetic retinopathy: An in silico and in vivo approach.

Chiara Bianca Maria PlataniaRosa MaistoMaria Consiglia TrottaMichele D'AmicoSettimio RossiCarlo GesualdoGiovanbattista D'AmicoCornel BaltaHildegard HermanAnca HermeneanFranca FerraraccioIacopo PanareseFilippo DragoClaudio Bucolo
Published in: British journal of pharmacology (2019)
Serum and retina of diabetic mice express eight dysregulated miRNAs, which modified the expression of VEGF, BDNF, PPAR-α, and CREB1, before vasculopathy in diabetic retinas.
Keyphrases
  • diabetic retinopathy
  • optical coherence tomography
  • poor prognosis
  • type diabetes
  • binding protein
  • endothelial cells
  • molecular docking
  • vascular endothelial growth factor
  • long non coding rna