Leishmania braziliensis causing human disease in Northeast Brazil presents loci with genotypes in long-term equilibrium.

Juliana A SilvaAna Isabelle PinheiroMaria Luiza DouradoLilian MedinaAdriano QueirozLuiz Henrique GuimarãesMarcus Miranda LessaEdnaldo L LagoPaulo Roberto Lima MachadoMary E WilsonEdgar Marcelino de Carvalho Albert Schriefer

Published in: PLoS neglected tropical diseases (2022)

These findings suggest that L. braziliensis can maintain stable populations in foci of human leishmaniasis and are capable of robust genetic recombination possibly due to events of sexual reproduction during the parasite's lifecycle.

Keyphrases

endothelial cells
induced pluripotent stem cells
genome wide
pluripotent stem cells
dna damage
molecular dynamics
dna repair
gene expression
molecular dynamics simulations
copy number
oxidative stress
plasmodium falciparum