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The Continuous Fragility Index of Statistically Significant Findings in Randomized Controlled Trials That Compare Interventions for Anterior Shoulder Instability.

Mohammed Al-AsadiMichelle SherrenHassaan Abdel KhalikTimothy LerouxOlufemi R AyeniKim MaddenMoin Khan
Published in: The American journal of sports medicine (2024)
More than a third of continuous outcomes in ASI trials had a CFI less than the reported loss to follow-up. This carries the significant risk of reversing trial findings and should be considered when evaluating available RCT data. We recommend including the FI, CFI, and loss to follow-up in the abstracts of future RCTs.
Keyphrases
  • randomized controlled trial
  • study protocol
  • clinical trial
  • electronic health record
  • physical activity
  • phase iii
  • big data
  • phase ii
  • machine learning
  • metabolic syndrome
  • artificial intelligence