Mechanical thrombectomy alone versus with thrombolysis for ischemic stroke: A meta-analysis of randomized trials.
Kobeissi HassanGautam AdusumilliSherief A GhozyCem BilginRamanathan D KadirvelWaleed BrinjikjiNicholas J LeeperAlejandro A RabinsteinDavid F KallmesPublished in: Interventional neuroradiology : journal of peritherapeutic neuroradiology, surgical procedures and related neurosciences (2023)
In this meta-analysis of six RCTs, MT alone was comparable to MT plus IVT for mRS 0-2, sICH, mortality, and distal embolization; however, MT alone resulted in lower rates of TICI 2b-3. Further trials are needed to determine which patient populations benefit from MT plus IVT and to increase the power of future meta-analyses.