Co-transplantation of human adipose-derived mesenchymal stem cells with neonatal porcine islets within a prevascularized subcutaneous space augments the xenograft function.
Purushothaman KuppanKaren SeebergerSandra KellyMandy RoskoAdetola AdesidaAndrew R PepperGregory S KorbuttPublished in: Xenotransplantation (2020)
Thus, our study demonstrates that co-transplantation of human AdMSCs with NPIs is an effective tactic to augment islet xenograft function in a clinically relevant extrahepatic site.