Increasing Immune Dysfunction is Associated with Increasing Matrix-Metalloproteinase-2 Expression and Predicts Biochemical Failure in Men with Bone Marrow Micro-Metastasis Positive Localized Prostate Cancer.
Nigel P MurraySocrates AedoCynthia FuentealbaEduardo ReyesAnibal SalazarPublished in: Asian Pacific journal of cancer prevention : APJCP (2022)
the immune host-tumour cell interaction in the microenvironment is dynamic and changes with time. A decreasing ALC may be a valuable marker in identifying men with high risk of BF and changes in immune mediated dormancy before the PSA rises.