Comparison of the Efficacy and Safety of Non-vitamin K Antagonist Oral Anticoagulants with Warfarin in Atrial Fibrillation Patients with a History of Bleeding: A Systematic Review and Meta-Analysis.

Boon-Hao SuahZhi-Yan LeeYao Hao TeoYao Neng TeoNicholas L X SynRodney Y H SohLeonard L L YeoBenjamin Y Q TanJamie Sin-Ying HoTony Y W LiChi-Hang LeeMark Y ChanTiong-Cheng YeoRaymond C C WongPing ChaiChing-Hui Sia

Published in: American journal of cardiovascular drugs : drugs, devices, and other interventions (2022)

NOACs showed better efficacy and safety profile compared with warfarin in patients with AF and a history of bleeding. Randomized controlled trials are warranted to validate these findings.

Keyphrases

oral anticoagulants
atrial fibrillation
left atrial
catheter ablation
direct oral anticoagulants
left atrial appendage
randomized controlled trial
heart failure
percutaneous coronary intervention
acute coronary syndrome