Dysregulation of long non-coding RNA gene expression pathways in monocytes of type 2 diabetes patients with cardiovascular disease.
Najeeb HalabiBinitha ThomasOmar ChidiacAmal RobayJulien AbiNahedAmin JayyousiJassim Al SuwaidiMartina BradicCharbel Abi KhalilPublished in: Cardiovascular diabetology (2024)
We identified dysregulated diabetes-related genes and pathways in monocytes of diabetes patients with cardiovascular complications, including lncRNA genes of unknown function strongly associated with networks of known diabetes genes.
Keyphrases
- type diabetes
- cardiovascular disease
- long non coding rna
- glycemic control
- gene expression
- poor prognosis
- genome wide
- dendritic cells
- dna methylation
- insulin resistance
- peripheral blood
- cardiovascular events
- cardiovascular risk factors
- bioinformatics analysis
- skeletal muscle
- coronary artery disease
- long noncoding rna
- genome wide analysis