Diabetic Ketoacidosis and Related Events With Sotagliflozin Added to Insulin in Adults With Type 1 Diabetes: A Pooled Analysis of the inTandem 1 and 2 Studies.
Anne L PetersDarren K McGuireThomas P A DanneJake A KushnerHelena W RodbardKetan K DhatariyaSangeeta SawhneyPhillip BanksWenjun JiangMichael J DaviesPablo LapuertaPublished in: Diabetes care (2020)
In patients with type 1 diabetes, confirmed DKA incidence increased when sotagliflozin was added to insulin compared with insulin alone. A lower incidence of DKA was observed following the implementation of an enhanced risk mitigation plan, suggesting that this risk can be managed with patient education.