Clinical evaluation of type 2 disease status in a real-world population of difficult to manage asthma using historic electronic healthcare records of blood eosinophil counts.
Adnan AzimColin NewellClair BarberMatthew HarveyDeborah KnightAnna FreemanWei Chern Gavin FongPaddy DennisonHans Michael HaitchiRatko DjukanovicRamesh KurukulaaratchyPeter HowarthPublished in: Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology (2021)
This highlights the central role that type 2 inflammation, as indicated by blood eosinophilia, has in difficult asthma and suggests that longitudinal electronic healthcare record analysis can be an important tool in clinical asthma phenotyping, providing insight that may help understand disease progression and better guide more specific treatment approaches.