CRISPR-based assays for low-resource settings.
Zhen HuangChristopher J LyonTony Ye HuPublished in: Nature reviews bioengineering (2023)
CRISPR-based assays can be adopted as ultrasensitive molecular diagnostics in resource-limited settings, but point-of-care applications must address additional requirements. Here, we discuss the major obstacles for developing these assays and offer insights into how to surmount them.