Breast cancer hypoxia in relation to prognosis and benefit from radiotherapy after breast-conserving surgery in a large, randomised trial with long-term follow-up.
Julia TutzauerMartin SjöströmErik Carl Viktor HolmbergPer KarssonFredrika KillanderL M Fredrik Leeb-LundbergPer MalmströmEmma NimeúsMårten FernöAnnika JögiPublished in: British journal of cancer (2022)
The benefit of postoperative radiotherapy persisted in patients with hypoxic primary tumours. Patients with hypoxic primary breast tumours had an increased risk of recurrence and breast cancer death.
Keyphrases
- early stage
- locally advanced
- minimally invasive
- radiation therapy
- radiation induced
- neoadjuvant chemotherapy
- patients undergoing
- coronary artery bypass
- squamous cell carcinoma
- study protocol
- randomized controlled trial
- rectal cancer
- coronary artery disease
- young adults
- percutaneous coronary intervention
- early breast cancer