[Possibilities of dynamic phase contrast MRI of cerebrospinal fluid for performing a tap test in a patient with idiopathic normotensive hydrocephalus].
D V NikitinM B DolgushinA V DvoryanchikovT M RostovtsevaIlya V SenkoR T TairovaPublished in: Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova (2024)
Idiopathic normotensive hydrocephalus (iNH) is a widespread disease in elderly patients. The effectiveness of iNG treatment and the subsequent quality of patients' lives directly depends on timely and early diagnosis. The criteria for diagnosing iNG that are used in neuroimaging can also be found in patients without clinical manifestations of this disease, and the widely used tap-test is an invasive technique with a rather low sensitivity. The need for early diagnosis and initiation of treatment before the development of irreversible damage to brain structures determines the relevance of the search for an accessible, minimally invasive, accurate and safe diagnostic method. The article presents a clinical observation of the use of phase-contrast MRI of cerebrospinal fluid (CSF) in a female patient with a positive response to the tap test with a quantitative analysis of changes in CSF flow parameters and ALVI and Evans indices depending on the time after CSF evacuation. Phase-contrast MRI of CSF with a quantitative assessment of CSF flow parameters in combination with an assessment of the ALVI index has the potential to increase the accuracy of diagnosing iNH and is of scientific interest for further research.
Keyphrases
- cerebrospinal fluid
- contrast enhanced
- end stage renal disease
- magnetic resonance imaging
- magnetic resonance
- ejection fraction
- minimally invasive
- newly diagnosed
- chronic kidney disease
- randomized controlled trial
- peritoneal dialysis
- high resolution
- computed tomography
- subarachnoid hemorrhage
- mass spectrometry
- diffusion weighted imaging
- white matter
- climate change
- brain injury
- cerebral ischemia
- resting state