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Real-world outcomes for 205 patients with chronic lymphocytic leukemia treated with ibrutinib.

Kathrine AarupEmelie Curovic RotbainLisbeth EnggaardRobert Schou PedersenOlav Jonas BergmannRasmus Heje ThomsenMikael FrederiksenHenrik FrederiksenTine NielsenIlse ChristiansenMichael Asger AndersenCarsten Utoft Niemann
Published in: European journal of haematology (2020)
In our study, we find comparable, though slightly inferior, overall, and progression-free survival, and discontinuation due to toxicity was higher compared with clinical trials. Patient training and information may improve treatment adherence outside clinical trials.
Keyphrases
  • chronic lymphocytic leukemia
  • clinical trial
  • free survival
  • oxidative stress
  • randomized controlled trial
  • open label
  • health information
  • metabolic syndrome
  • double blind
  • replacement therapy
  • newly diagnosed