Serum GFAP and NfL as disease severity and prognostic biomarkers in patients with aquaporin-4 antibody-positive neuromyelitis optica spectrum disorder.
Patrick SchindlerUlrike GrittnerJohanna OechteringDavid LeppertNadja SiebertAnkelien S DuchowFrederike C OertelSusanna AsseyerJoseph KuchlingHanna G ZimmermannAlexander U BrandtPascal BenkertMarkus ReindlSven JariusFriedemann PaulJudith Bellmann-StroblJens KuhleKlemens RuprechtPublished in: Journal of neuroinflammation (2021)
These findings suggest a potential role for sGFAP as biomarker for disease severity and future disease activity in patients with AQP4-IgG+ NMOSD in phases of clinical remission.