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SGLT2 inhibitors in patients with type 2 diabetes with non-alcoholic fatty liver diseases: an umbrella review of systematic reviews.

Shih-Chieh ShaoLiang-Tseng KuoRong-Nan ChienMing-Jui HungEdward Chia-Cheng Lai
Published in: BMJ open diabetes research & care (2021)
There is some association between SGLT2 inhibitor use and observed benefits to liver functions in patients with T2D with NAFLD, although the quality of current systematic reviews remains relatively low. Further evaluation of long-term liver outcomes with SGLT2 inhibitors in cases of liver cirrhosis and liver cancer is warranted.
Keyphrases
  • systematic review
  • meta analyses
  • type diabetes
  • randomized controlled trial
  • liver injury
  • quality improvement
  • skeletal muscle