Engaging Cancer Care Physicians in Off-Label Drug Clinical Trials: Human-Centered Design Approach.
Maren C ParsellMorgan N GreenleafGreeshma G KombaraVikas P SukhatmeWilbur A LamPublished in: JMIR formative research (2024)
Using participatory HCD methods, we delivered 3 concepts for clinical trial support resources to help physician stakeholders overcome barriers to pursuing clinical trials for OLDs to treat cancer. Overall, integrating the HCD approach can aid in identifying important stakeholders, such as prescribing physicians; facilitating their engagement; and incorporating their perspectives and needs into the solution design process. This paper highlights the process, methods, and potential of HCD to improve cancer clinical trial design. Future work is needed to train clinical trial designers in the HCD approach and encourage adoption in the field.
Keyphrases
- clinical trial
- primary care
- papillary thyroid
- phase ii
- open label
- double blind
- squamous cell
- endothelial cells
- phase iii
- study protocol
- emergency department
- lymph node metastasis
- randomized controlled trial
- squamous cell carcinoma
- current status
- childhood cancer
- electronic health record
- young adults
- risk assessment
- adverse drug
- mass spectrometry
- placebo controlled