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Pulmonary inflammatory response and immunomodulation to multiple trauma and hemorrhagic shock in pigs.

Marc-Alexander OestreichKerstin SeidelWilhelm BertramsHans-Helge MüllerMartin SassenThorsten SteinfeldtHinnerk WulfWilhelm Bertrams
Published in: PloS one (2022)
We observed signs of a time-dependent pulmonary inflammation and apoptosis at the site of severe trauma, and to a lower extent in the trauma-distant lung. Intervention with mild hypothermia had no considerable effect during 48 hours following trauma.
Keyphrases
  • inflammatory response
  • trauma patients
  • oxidative stress
  • pulmonary hypertension
  • randomized controlled trial
  • lymph node
  • early onset
  • signaling pathway