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An integrated analysis of herpes virus infections from eight randomized clinical studies of baricitinib in adults with moderate-to-severe atopic dermatitis.

T WerfelA D IrvineC BangertJulien SeneschalS GrondT CardilloD BrinkerJ ZhongE RiedlAndreas Wollenberg
Published in: Journal of the European Academy of Dermatology and Venereology : JEADV (2022)
TE-herpes simplex was common, while occurrence of EH was uncommon. Most events of EH were localized with involvement of a small BSA and were linked to poor disease control. Events of HZ were rare in the PC dataset and without a dose dependent increase in frequency.
Keyphrases
  • atopic dermatitis
  • double blind
  • open label
  • risk assessment
  • herpes simplex virus
  • phase iii
  • high intensity
  • early onset
  • phase ii
  • clinical trial
  • randomized controlled trial
  • study protocol