Expressions of extracellular matrix-remodeling factors in lymph nodes from oral cancer patients.
Shuichi FujitaMisa SumiEri TatsukawaKenichi NaganoNaoki KatasePublished in: Oral diseases (2020)
Expression of LOX, MT1-MMP, and TIMP-1 in the parenchyma, and stromal expression of TIMP-1 in primary tumor may predict lymphatic metastasis. LOX and MT1-MMP have a possibility to participate in formation of pre-metastatic niche in LNs.