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Similar glycaemic control and less hypoglycaemia during active titration after insulin initiation with glargine 300 units/mL and degludec 100 units/mL: A subanalysis of the BRIGHT study.

Alice Y Y ChengStewart HarrisFrancesco GiorginoJochen SeufertRobert RitzelKamlesh Khunti F MedSciFelipe LauandLydie Melas-MeltJukka WesterbackaZsolt BosnyakJulio Rosenstock
Published in: Diabetes, obesity & metabolism (2019)
The use of Gla-300 resulted in similar glycaemic control as IDeg-100 during the initial 12-week titration period of the BRIGHT study, when less anytime (24 hours) hypoglycaemia with Gla-300 versus IDeg-100 has been reported. Experiencing hypoglycaemia shortly after initiating Gla-300 or IDeg-100 may be associated with hypoglycaemia incidence in the longer term, potentially impacting glycaemic management.
Keyphrases
  • type diabetes
  • glycemic control
  • insulin resistance
  • randomized controlled trial
  • risk factors
  • preterm infants
  • clinical trial