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Inhibition of Aurora B kinase (AURKB) enhances the effectiveness of 5-fluorouracil chemotherapy against colorectal cancer cells.

Esha T ShahChristopher MolloyMadeline GoughThomas KryzaSelwin G SamuelAmos TuckerManeet BhatiaGenevieve FergusonRebecca HeymanShivam VoraJames MonkmanEmma BoldersonArutha KulasingheYaowu HeBrian G GabrielliJohn D HooperDerek J RichardKenneth J O'ByrneMark Nathaniel Adams
Published in: British journal of cancer (2024)
AURKB inhibition may be a rational approach to augment the effectiveness of 5-FU chemotherapy in CRC.
Keyphrases
  • randomized controlled trial
  • systematic review
  • locally advanced
  • tyrosine kinase
  • protein kinase